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Anticancer potential of nanogold conjugated toxin GNP-NN-32 from Naja naja venom J. Venom. Anim. Toxins incl. Trop. Dis.
Attarde,Saurabh S.; Pandit,Sangeeta V..
Abstract Background: Cancer is the second most common fatal disease in the world, behind cardiovascular disorders in the first place. It accounts for around 0.3 million deaths per year in India due to the lack of proper diagnostic facilities, prevention and treatment. Current therapeutic methods do not provide adequate protection and affect normal cells along with cancerous ones. Thus, there is a need for some alternative therapeutic strategy, preferably from natural products, which have been traditionally used for treatment of various diseases in the country. Methods: In this study, we have conjugated purified NN-32 toxin from Naja naja venom with gold nanoparticles and its anticancer potential was evaluated against human breast cancer cell lines....
Tipo: Info:eu-repo/semantics/article Palavras-chave: GNP-NN-32; Anticancer; Toxin; Naja naja; Venom; Breast cancer; MCF-7; MDA-MB-231.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100304
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